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A hearty casserole of baked Southern chicken spaghetti topped with melted cheese and fresh herbs, serving as a comforting family meal.

Zesty Southern Chicken Spaghetti Bake: A Comfort Food Masterpiece

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Discover the deliciousness of Zesty Southern Chicken Spaghetti Bake, a spicy and creamy casserole that combines tender chicken, flavorful spices, and cheesy goodness for a comforting Southern-inspired meal everyone will love.

  • Total Time: 40 minutes
  • Yield: 6 servings

Ingredients

Scale
  • 2 cups cooked chicken, shredded or cubed
  • 12 oz spaghetti or your favorite pasta
  • 1 cup diced bell peppers (red or green)
  • 1 medium onion, chopped
  • 3 cloves garlic, minced
  • 2 cups shredded sharp cheddar cheese
  • 1 cup sour cream or Greek yogurt
  • 1 can (10 oz) diced tomatoes with green chiles
  • 1 tsp smoked paprika
  • 1/2 tsp cayenne pepper (adjust to taste)
  • 1/2 tsp black pepper
  • Salt to taste
  • Fresh parsley, chopped (for garnish)
  • Olive oil for sautéing

Instructions

  1. Cook spaghetti in boiling salted water until al dente; drain and set aside.
  2. In a skillet, heat olive oil over medium heat. Sauté onions and peppers until softened, then add garlic and cook for another minute.
  3. Add diced tomatoes with green chiles, smoked paprika, cayenne pepper, salt, and black pepper. Simmer for 5 minutes.
  4. In a large bowl, combine cooked pasta, chicken, sautéed vegetables, and the tomato mixture. Stir in sour cream or Greek yogurt and most of the shredded cheese.
  5. Transfer to a greased baking dish. Top with remaining cheese.
  6. Bake at 375°F (190°C) for 20-25 minutes until bubbly and golden brown.

Notes

  • Feel free to adjust spice levels by increasing or decreasing cayenne pepper.
  • You can substitute Greek yogurt for sour cream for a healthier option.
  • Leftovers can be stored in an airtight container for up to 3 days, reheat in the microwave or oven.
  • Author: Emma Bloomfield
  • Prep Time: 15 minutes
  • Cook Time: 25 minutes
  • Category: Main Dish
  • Method: Bake
  • Cuisine: Southern American
  • Diet: Nut-Free

Nutrition

  • Serving Size: 1 plate
  • Calories: 520 kcal Kcal
  • Sugar: 7 g
  • Sodium: 920 mg
  • Fat: 22 g
  • Saturated Fat: 11 g
  • Unsaturated Fat: 8 g
  • Trans Fat: 0 g
  • Carbohydrates: 60 g
  • Fiber: 5 g
  • Protein: 36 g
  • Cholesterol: 125 mg